How Does Topiramate Contribute to the Weight Loss Process in Various Topiramate/Phentermine Combinations

For people trying to lose weight it is often difficult to control their appetite and the feeling of hunger. Topiramate and Phentermine proved to be an effective combination for suppressing appetite and food cravings. It is important to note that these drugs should be used together with a low calorie diet and regular exercising. Separately, Phentermine helps patients to control their appetite and Topiramate is usually used as an anticonvulsant drug, also preventing migraine headaches.However, even though separate Topiramate weight loss effect is claimed to be one of the drug’s side effects, in 2012 FDA approved it as a weight-loss drug if taken together with Phentermine.

The most well-known drug that includes both Topiramate and Phentermine is Qsymia. It is prescribed to patients with a BMI of 30 or more, as well as to to the ones with a BMI 27 or more if they have at least one weight-related problem (high blood pressure, high cholesterol or type 2 diabetes). The dosage of Qsymia, Topiramate and Phentermine combination, varies, but usually it is taken once a day in the morning. It is recommended to start with the dose of 3.75mg of Phentermine and 23 mg of Topiramate. In 14 days the dosage should be increased to 7.5mg of Phentermine and 46 mg of Topiramate. The further increase of the dosage is possible, taking into account the percentage of weight loss and doctor’s recommendations.

In spite of the fact that most of the patients use Topiramate and Phentermine for weight loss purposes, some patients prefer to stick to Topiramate only. Topiramate (branded under the name Topamax) has been reported by many patients as a drug helping to lose weight. Topiramate helps patients to control their appetite that is useful alongside with a reduced calorie diet and regular work out. Also many patients mentioned that sometimes when they used Topiramate, weight loss occurred faster because the drug affected their sense of taste and they ate less, as a consequence.

Normally, patients start with a low dose of Topiramate – 25mg with the duration of use advised by their physician, that can last for a few months and more. But since patients taking this drug appear to be dose-dependent, the dosage is increased in order to keep the same level of weight loss or even increase it. For example, some patients moved to Topiramate 100mg, after taking 50mg pills twice a day, for keeping or improving the effect, and to 200mg a day for the same purpose. The initial and increased dosage usually depends on patient’s weight and eating habits.

The success of Topiramate and Phentermine combination is also determined by the fact that Topiramate has the ability to prolong the feeling of satiety, thus not allowing patients to eat as often as they used to.

Before starting the treatment with Topiramate – 25mgor any other dosage of this medication, patients should make sure their doctor knows about any drugs they are taking (both prescribed and non-prescribed), and also if they are allergic to Topiramate or any of its inactive components. Patients should also let their doctor know if they have or ever had: glaucoma, kidney problems, signs of kidney stones (such as fever, chills, painful or frequent urination, back/abdominal or groin pain, bloody or pink urine), liver problems, mental or mood problems (sudden or unusual changes of thoughts and mood, changes in behavior including depression, suicidal thoughts and/or attempts) metabolic imbalance, fast/slow or irregular heartbeat, unusual bleeding or bruising, osteoporosis and if they are on a ketogenic diet (high in fat and low in carbohydrates). Pregnant women should not take Topiramate – weight loss caused by the medication, as well as other effects it has on the body, might be harmful for the fetus. It is also not recommended to use Topiramate during pregnancy, as there are no adequate studies on whether Topiramate is secreted in human breast milk. Patients should consult their physician before breastfeeding as there is a possibility that the drug passes into breast milk and may eventually harm the baby.

Topiramate can cause different side-effects. Besides the above-mentioned changes in taste and weight loss, the drug can also cause:

  • Tiredness
  • Loss of coordination
  • Diarrhea
  • Confusion
  • Trouble concentrating
  • Attention problems
  • Nervousness
  • Changes in vision
  • Problems with speech
  • Problems with memory
  • Hair loss

Topiramate can make patients feel dizzy and it is not recommended to drink alcohol or use marijuana together with Topiramate, as they can worsen this effect. Patients should address their doctor if they feel unwell, have mental or mood changes, headache, dizziness or have a fever that does not go away for a long period of time.

Patients are often wondering if they can buy Topiramate online and what would the alternatives of this drug be. The usual result given while searching for Topiramine is the drug Topamax. Topamax/Topiramate (manufacturer Janssen Pharmaceuticals, now part of Johnson & Johnson Health Care Systems Inc.) is available online in different dosages. Patients can order Topiramate online in 25mg, 50mg, 100mg, 200 mg pills in online drugstores. The prices vary depending on the dosage and quantity. Thus, 120 tablets of Topamax 25mg cost $64.99 and 120 tablets of Topamax 50mg are sold at $98.99.

There are generic equivalents for Topamax available on the market as well. Some patients tend to buy them because they are more affordable. In comparison with Topamax, 120 pcs of Topiramate generic 50mg pills cost only $21.99. There are no major differences in side-effects or contradictions of generic Topiramate and Topamax and often namely the contrast in price makes patients choose Topiramate generic version over the branded one.

It is to be noted that the usual search provides the options of buying Topiramate in the US and Canada. European options are limited to the Online Pharmacy where patients can order the drug, but at a much higher price. Patients in Europe should be watchful when they decide to buy Topiramate online .uk, .de, and .it websites on the search page are currently leading to the Online Pharmacy.

It should be pointed out that even though many online drugstores offer to buy Topiramate without a prescription, patients should consult their physician in order to avoid any possible risks. Starting any treatment without a valid prescription from a qualified specialist may result in harm to one’s health.