Combination of Phentermine and Topiramate for Weight Loss

Phentermine/Topamax combination is used as a weight-management medication that is prescribed to overweight or obese people, who also have one or several medical conditions related to excessive weight. The extended-release capsules of Phentermine and Topamax are recommended for use together with a low-calorie diet and increased physical activity. Phentermine works as an appetite suppressant as it belongs to a class of anorectics, while Topamax (generic name – Topiramate) is an anticonvulsant drug. Topamax and phentermine, taken together, reduce a person’s appetite and prolong the feeling of satiety.

The medications are to be taken by mouth once a day, usually in the morning, because if taken in the evening, they could prevent you from sleeping well or falling asleep at all. You can take the extended-release capsules with disregard to meals. The effective Phentermine/Topiramate dosage differs from a person to person, but the usual starting dose is a low one – 37.5 mg of Phentermine and 23 mg of Topiramate. After a week or two, your doctor will probably recommend you to increase the dose, as the starting one might not be effective. Do not increase Phentermine/Topamax dosage on your own without your doctor’s recommendation. As a rule, you should undergo a check after 12 weeks of the treatment and depending on whether or not you lost some weight or what amount you lost, your doctor will either recommend you to continue with the same dose, increase it, or stop taking the medication. If after the first 12 weeks, your Phentermine/Topamax dosage was increased, then the following 12 weeks will be decisive. If during this period you have not lost the necessary amount of weight, you should stop taking the medication.

In case of a missed dose, just take your next dose as usual the following day. Do not double the dose even if you miss one.
Phentermine/Topamax weight loss pills can cause addiction, so you must not take them more often, take a higher dose, or continue the treatment for longer than your doctor advised.

At the end of the treatment, the dosage should be gradually reduced. Do not stop taking the medication abruptly as this might cause seizures. Talk to your doctor and follow their instructions on how to reduce the dosage before you stop taking the medication completely.

Before you start taking Topamax/Phentermine diet pills, you should inform you doctor if you are allergic or have ever had an allergic reaction to Topiramate; Phentermine; Midorine, Phenylephrine, or any ingredients contained in Phentermine/Topamax weight loss pills.

If you are currently taking any of the following medications or took any of them in the past few weeks, you should inform your doctor about it: Phenelzine (Nardil), Selegiline (Emsam, Zelapar, Eldepryl), monoamine oxidase inhibitors, and Tranylcypromine (Parnate). Topamax and Phentermine taken together with any these medications can cause serious adverse reactions.

Do avoid possible drug interactions, tell you doctor about all the medications you are currently taking, including other weight loss drugs, vitamins, and herbal supplements. If you need to take some drugs that might interact with Topamax/Phentermine diet pills, your doctor might adjust the dosage of your medications and should warn you about the possible side effects.

It is not recommended to take Phentermine/Topamax combination if you have glaucoma or hyperthyroidism, so if you suffer from any of these conditions, inform your doctor about it.

The following conditions might be a contraindication to taking Phentermine and Topamax, so your doctor should know about them: heart attack or a stroke during the past 6 months, heart failure, irregular heartbeat, seizures, depression, thoughts about suicide, metabolic acidosis, diabetes, kidney or liver problems, and diarrhea. Many of these are listed as Phentermine/Topamax side effects, so taking the medication while you have any of these conditions, could seriously aggravate their manifestation.

Your doctor should know if you are pregnant or planning to get pregnant in the nearest time as in this case, you must not take the medication. Phentermine/Topiramate combination can cause serious birth defects, even if you take the medication at an early stage of your pregnancy when you might not even know that you are pregnant. Take a pregnancy test before the start of the treatment and use safe birth control methods while you are taking the medication. Topamax/Phentermine diet pills do not interact with oral contraceptives, so they can be safely used during the treatment. Breastfeeding while on Topamax and Phentermine could be dangerous, as the medication might pass into breast milk and harm the baby.

Phentermine/Topiramate side effects can be manifested on both psychological and physiological levels. There have been reports from people who took Topamax, about behavioral changes, mood swings, and even suicide thoughts and suicide attempts. Any of the following manifestations should be a sign for you to address your doctor immediately: restlessness, agitation, irritability, mood changes, panic attacks, aggressiveness, violent behavior, anger, anxiety, depression, suicidal thoughts, thoughts about hurting other people, mania, or any other uncharacteristic behavior. Your family members should know what the possible Phentermine/Topamax side effects are in order to be able to help you and call your doctor in case you are not able to do it yourself.

Other Phentermine/Topamax side effects that the users have reported are dizziness, headache, tingling in the extremities, dry mouth and unusual thirst, tiredness, constipation, loss of concentration, diarrhea, changes in the tasting sensation, hair loss. Many people reported that these side effects, although quite unpleasant, usually pass after a few weeks since the start of the treatment.
Dangerous side effects of the medication include eye redness or pain in the eyes, changes in vision, increased heart rate, blood in the urine, severe back pain, and hives. The medication can also cause other side effects, so you should carefully monitor any changes in your mental or physical health and report them to your doctor.

Topamax/Phentermine cost might seem high because of the price on branded Topamax, its average price being around $83 for 15 tablets 25 mg each. To compare – the price of Topiramate is around $30 for 20 capsules 25 mg each. The price you would have to pay for Phentermine is $20.5 for 30 capsules of 37.5 mg dosage. You can also save money on Topamax/Phentermine cost by printing online coupons that will allow you to buy the medications at a discounted price.